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Thanks to https://wordpress.org/support/users/knutsp/, https://wordpress.org/support/users/jilfransoi/, https://wordpress.org/support/users/aumw-jay/.
Both knutsp and aumw-jay reported a crash with PHP8 and jilfransoi provided a work-around fix.
Uncaught TypeError: is_file(): Argument #1 ($filename) must be of type string, GdImage given in /home/*/public_html/wp-content/plugins/auto-smart-thumbnails/inc/class-ast-face-detector.php:63
The problem was explained here: https://php.watch/versions/8.0/gdimage. It’s fixed per this explanation.