REDIS / NGINX caching

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Wondering if the plugin would work on a setup where we run Redis object cache / NGINX page cache and a modified WP-rocket setup on a NGINX server.
How much does WP do and how much this plugin.
More or less related, how does this adds/interferes with pagebuilders like Elementor where you can set already different sizes (but not everybody does).
Just curious if it is worth the extra overhead.